Name | 2,4,6-Collidine |
Synonyms | S-Collidine g-Collidine sym.-collidine 2,4,6-Kollidin 2,4,6-Collidine a,g,a'-Collidine 2,4,6-Trimethylpyridine 2,4,6-trimethyl-pyridin 2,3,4-trimethylpyridine 2,4,6-trimethyl-pyridine Pyridine,2,4,6-trimethyl- 2 Minus 2-3 Methyl pyridine alpha,gamma,alpha'-Collidine alpha,gamma,alpha'-collidine |
CAS | 108-75-8 |
EINECS | 203-613-3 |
InChI | InChI=1/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3 |
Molecular Formula | C8H11N |
Molar Mass | 121.18 |
Density | 0.917 g/mL at 25 °C (lit.) |
Melting Point | -43 °C (lit.) |
Boling Point | 171-172 °C (lit.) |
Flash Point | 135°F |
Water Solubility | 35 g/L (20 ºC) |
Solubility | 35g/l |
Vapor Presure | 4 hPa (20 °C) |
Appearance | Liquid |
Color | Clear colorless to yellow |
Merck | 14,9718 |
BRN | 107283 |
pKa | 7.43(at 25℃) |
Storage Condition | Store below +30°C. |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Sensitive | Hygroscopic |
Refractive Index | n20/D 1.498(lit.) |
Physical and Chemical Properties | Boiling point 171~172 ℃ relative density 0.917g/cm3 refractive index 1.4980 |
Use | For Organic synthesis |
Hazard Symbols | Xn - Harmful |
Risk Codes | R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. |
UN IDs | UN 1992 3/PG 3 |
WGK Germany | 3 |
RTECS | UU0970000 |
TSCA | Yes |
HS Code | 29333999 |
Hazard Class | 3 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 400 mg/kg |
Raw Materials | Benzene Ammonia Sulfuric acid |
LogP | 1.25 at 20℃ |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
application | 2,4, 6-trimethylpyridine can be used as a standard substance for chromatographic analysis, as well as as a solvent for organic synthesis. It can mainly be used as an effective solvent for anhydrous lithium iodide to cleave sterically hindered esters and as a tissue fixative for electron microscopy. |
Use | Used in organic synthesis Used as a standard substance for chromatographic analysis, also used as a solvent, organic synthesis. An effective solvent for anhydrous lithium iodide to crack sterically hindered esters. Used as a tissue fixative for electron microscopy. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |